Search on: NM23 NUCLEOSIDE DIPHOSPHATE KINASES 
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Descriptor English:   NM23 Nucleoside Diphosphate Kinases 
Descriptor Spanish:   Nucleósido Difosfato Quinasas NM23 
Descriptor Portuguese:   Nucleosídeo NM23 Difosfato Quinases 
Synonyms English:   Nucleoside Diphosphate Kinase A  
Tree Number:   D08.811.913.696.650.550.200
Definition English:   A family of nucleotide diphosphate kinases that play a role in a variety of cellular signaling pathways that effect CELL DIFFERENTIATION; CELL PROLIFERATION; and APOPTOSIS. They are considered multifunctional proteins that interact with a variety of cellular proteins and have functions that are unrelated to their enzyme activity. 
History Note English:   2008(1989) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52747 
Unique Identifier:   D054778 

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